Training in High-Throughput Sequencing: Common Guidelines to Enable Material Sharing, Dissemination, and Reusability

نویسندگان

  • Bastian Schiffthaler
  • Myrto Kostadima
  • NGS Trainer Consortium
  • Nicolas Delhomme
  • Gabriella Rustici
چکیده

The advancement of high-throughput sequencing (HTS) technologies and the rapid development of numerous analysis algorithms and pipelines in this field has resulted in an unprecedentedly high demand for training scientists in HTS data analysis. Embarking on developing new training materials is challenging for many reasons. Trainers often do not have prior experience in preparing or delivering such materials and struggle to keep them up to date. A repository of curated HTS training materials would support trainers in materials preparation, reduce the duplication of effort by increasing the usage of existing materials, and allow for the sharing of teaching experience among the HTS trainers' community. To achieve this, we have developed a strategy for materials' curation and dissemination. Standards for describing training materials have been proposed and applied to the curation of existing materials. A Git repository has been set up for sharing annotated materials that can now be reused, modified, or incorporated into new courses. This repository uses Git; hence, it is decentralized and self-managed by the community and can be forked/built-upon by all users. The repository is accessible at http://bioinformatics.upsc.se/htmr.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Add-on for High Throughput Screening in Material Discovery for Organic Electronics: “Tagging” Molecules to Address the Device Considerations

This work reflects the worth of intelligent modeling in controlling the nanostructure morphology in manufacturing organic bulk heterojunction (BHJ) solar cells. It suggests the idea of screening the pool of material design possibilities inspired by machine learning. To fulfill this goal, a set of experimental data on a BHJ solar cell with a donor structure of diketopyrrolopyrrole (DDP) and ...

متن کامل

Enhancing Users' Participation in Business Process Modeling through Ontology-Based Training

Successful business process design requires active participation of users who are familiar with organizational activities and business process modelling concepts. Hence, there is a need to provide users with reusable, flexible, agile and adaptable training material in order to enable them instil their knowledge and expertise in business process design and automation activities. Knowledge reusab...

متن کامل

Strategic Planning for Information Resources: Enhancing Managers’ Participation through Ontology-based Modeling

Successful strategic planning for information resources (SPIR) requires active participation of managers-users who are familiar with the cooperative and collaborative nature of the strategic planning processes. Hence, there is a need to provide them with reusable, flexible, agile and adaptable training material in order to enable them instil their knowledge and expertise in the SPIR process and...

متن کامل

مروری برتکنیک های توالی یابی D‏NA (نسل اول، نسل دوم و نسل سوم)

Introduction: The DNA sequencing is the most important technique in molecular biology by which the order of the nucleotides can be identified in a piece of DNA. There are several different methods for sequencing the DNA. Now, the DNA sequencing has great importance in the medical diagnostics and other medical fields. Some methods have been invented to speed up and increase the efficiency of the...

متن کامل

Modeling & Simulation Challenges

© PrismTech, 2013 Modeling & Simulation Challenges The need to make Modeling & Simulation (M&S) environments more realistic and sophisticated so that they can support an increasingly varied and wide range of complex situations is driving the need for extremely high throughput, low latency, real-time data sharing over geographically dispersed distributed networks. This is combined with the need ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 12  شماره 

صفحات  -

تاریخ انتشار 2016